A case of significant weight loss and severe malnutrition caused by achalasia

Achalasia is caused by chronic degeneration of ganglionic cells in the myenteric plexus that leads to failure relaxation lower esophageal sphincter (LES). This aperistalsis digital esophagus and eventually led dilation esophagus. We present case a 37-year-old man who initially presented with dysphagia for solid food then slowly developed liquid over past 6 months. He had significant weight loss, his esophagogastroduodenoscopy (EGD) showed esophagitis gastritis. The imaging computed tomography (CT) oral contrast distal mild circumferential thickening at gastroesophageal junction. After response BoTox-infiltration LES, patient was taken Heller’s myotomy. immediate improvement after surgical intervention. study includes findings from CT scan, X-ray, EGD biopsies this patient. paper also summarizes therapeutic options BoTox-injection myotomy